Increased High-Density Lipoprotein Cholesterol Levels in Mice With XX Versus XY Sex Chromosomes
نویسندگان
چکیده
منابع مشابه
Increased high-density lipoprotein cholesterol levels in mice with XX versus XY sex chromosomes.
OBJECTIVE The molecular mechanisms underlying sex differences in dyslipidemia are poorly understood. We aimed to distinguish genetic and hormonal regulators of sex differences in plasma lipid levels. APPROACH AND RESULTS We assessed the role of gonadal hormones and sex chromosome complement on lipid levels using the four core genotypes mouse model (XX females, XX males, XY females, and XY mal...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2015
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.115.305460